Variable atrioventricular block in systemic lupus erythematosus
Identifieur interne : 001F34 ( Main/Exploration ); précédent : 001F33; suivant : 001F35Variable atrioventricular block in systemic lupus erythematosus
Auteurs : Sybille Liautaud [États-Unis] ; Ahmed J. Khan [États-Unis] ; Shireesha R. Nalamasu [États-Unis] ; Irene J. Tan [États-Unis] ; Anekwe E. Onwuanyi [États-Unis]Source :
- Clinical Rheumatology [ 0770-3198 ] ; 2005-04-01.
English descriptors
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Abstract
Abstract: Systemic lupus erythematosus (SLE), a connective tissue disease characterized by the production of auto-antibodies and immune complexes, can affect all organs including the heart. The involvement of the conduction system in SLE has been less commonly described. We report a case of an asymptomatic 45-year-old woman with SLE referred to the emergency department (ED) for thrombocytopenia, and was found to have alternating first- and second-degree atrioventricular block (AVB) during routine electrocardiographic screening for hospital admission. Serial electrocardiograms (ECG) done in the ED when compared to those recorded 24 h prior revealed progression from mild first-degree AVB (PR interval = 216 ms) to significant first-degree AVB (PR interval = 510 ms), followed by second-degree AVB (Mobitz type I—Wenckebach phenomenon). The conduction abnormalities recorded over a 28-h period resolved with corticosteroid treatment. Review of the literature on the disruption of the cardiac conduction system in SLE is discussed.
Url:
DOI: 10.1007/s10067-004-0995-3
Affiliations:
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The involvement of the conduction system in SLE has been less commonly described. We report a case of an asymptomatic 45-year-old woman with SLE referred to the emergency department (ED) for thrombocytopenia, and was found to have alternating first- and second-degree atrioventricular block (AVB) during routine electrocardiographic screening for hospital admission. Serial electrocardiograms (ECG) done in the ED when compared to those recorded 24 h prior revealed progression from mild first-degree AVB (PR interval = 216 ms) to significant first-degree AVB (PR interval = 510 ms), followed by second-degree AVB (Mobitz type I—Wenckebach phenomenon). The conduction abnormalities recorded over a 28-h period resolved with corticosteroid treatment. Review of the literature on the disruption of the cardiac conduction system in SLE is discussed.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li><li>Michigan</li><li>État de New York</li></region></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Liautaud, Sybille" sort="Liautaud, Sybille" uniqKey="Liautaud S" first="Sybille" last="Liautaud">Sybille Liautaud</name></region><name sortKey="Khan, Ahmed J" sort="Khan, Ahmed J" uniqKey="Khan A" first="Ahmed J." last="Khan">Ahmed J. Khan</name><name sortKey="Nalamasu, Shireesha R" sort="Nalamasu, Shireesha R" uniqKey="Nalamasu S" first="Shireesha R." last="Nalamasu">Shireesha R. Nalamasu</name><name sortKey="Onwuanyi, Anekwe E" sort="Onwuanyi, Anekwe E" uniqKey="Onwuanyi A" first="Anekwe E." last="Onwuanyi">Anekwe E. Onwuanyi</name><name sortKey="Tan, Irene J" sort="Tan, Irene J" uniqKey="Tan I" first="Irene J." last="Tan">Irene J. 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